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Vitamin B3 Niacin


Vitamin B3 Niacin

  • Required for energy metabolism, enzyme reactions, skin and nerve health, and digestion.
  • High doses of nicotinic acid (3 g daily) can lower cholesterol (reduce LDL and triglycerides and increase HDL) and reduce the risk of heart attack and stroke; high dosages should be supervised by a physician.
  • Deficiency causes pellagra, the symptoms of which are skin rash, diarrhea, dementia, and death.
  • Defi ciency may be caused by poor diet, malabsorption diseases, dialysis, and HIV.
  • Drugs that deplete vitamin B3: antibiotics, isoniazid, and 5-Fluorouracil (chemotherapy).
  • High-dose niacin, taken along with statin drugs (i.e., lovastatin), may increase the risk of rhabdomyolysis (muscle degeneration and kidney disease).
  • Most people get adequate niacin from diet and/or a multivitamin; supplements may be recommended for those with high cholesterol.

  • Food Sources : Fish, meat, poultry, dairy, nuts, seeds, whole grains, fortifi ed cereals
  • Adequate Intake : (mg/day)
    Men = 16
    Women = 14
    Pregnancy = 18
    Lactation = 17
  • Upper Limit : 35 mg/day
  • Side Effects : No adverse effects from niacin in foods; supplements may cause fl ushing and upset stomach; higher doses (500 mg/ day) may cause liver problems, particularly with time-release products

  • Vitamin A
    Vitamin B5 Pantothenic Acid
    Vitamin B12 Cobalamin
    Vitamin E
    Vitamin C Ascorbic Acid
    Vitamin B2 Ribofl avin
    Vitamin B6 Pyridoxine
    Vitamin B3 Niacin
    Vitamin D
    Folate Folic Acid
    Vitamin K
    More ...

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