Place a drop of paint at the bottom of the nail

Position the nail polish brush at the bottom of your nail, just above the cuticle, directly in the center. Allow a drop of paint (enough to cover your whole nail) to fall on this spot and pool slightly at the bottom of the nail. This is a technique used by professional manicurists, so it might take some practice, but eventually it will allow for the easiest and neatest polish application.